Vesiculobullous disease

Pemphigus Vulgaris

Autoimmune disorder

Painful skin bullae

*Ruptures EASILY*

**Positive Nikolsky Sign**

Tx: Steroids, Immunosuppressive therapy

Bullous Pemphigoid

Usually in elderly

Plaques that turn into painful skin bullae

*DOES NOT rupture easily*

**Negative Nikolsky Sign**

Tx: Steroids

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