Hemoglobinopathies
Hemochromatosis
Excess iron in body
**BRONZE DIABETES** due to pancreatic insufficiency
Liver biopsy gold standard to diagnose
Tx: Phlebotomy
Sickle Cell Disease
Amino acid Valine replaced by Glutamic Acid
During excessive stress and hypoxic conditions cells sickle causing organ damage and hemolytic anemia
**Aplastic Crisis in Parvovirus B19**
Priapism
Thalassemia
Thalassemia = decreased hemoglobin chains
Alpha vs Beta
Treatment depends on the severity and type
PANCE Prep Pearls has an incredible chart show the lab values and hemoglobin electrophoresis results to distinguish between alpha and beta-thalassemia
For additional questions and explanations click below!
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